sepsis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Patients diagnosed as sepsis according to the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3); (2) Patients required invasive mechanical ventilation for at least 5 days.
Exclusion criteria
Exclusion criteria: (1) age less than 18 years; (2) a previously diagnosed neuromuscular disorder; (3) Patients with central or peripheral nervous system injury; (4) impossibility to assess muscular strength in a limb because of amputation or immobilization; (5)antecedents of cognitive disorders that prevented the understanding of simple orders; (6) unwillingness of the patient or proxy to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Medical Research Council (MRC) Score;diaphragmatic thickening fraction(DTF);maximum inspiratory pressure(MIP); | — |
Secondary
| Measure | Time frame |
|---|---|
| durations of mechanical ventilation;Intensive care unit length of stay;ICU mortality; | — |
Countries
China
Contacts
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine