limited stage small cell lung cancer
Conditions
Interventions
Group 1:conventional fractionated intensity modulated radiotherapy (IMRT)
Group 2:simultaneous integrated boost intensity modulated radiotherapy
Sponsors
The First Hospital of Jilin University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Histological diagnosed limited stage small cell lung cancer; 2. ECOG 0-1; 3. Life expectancy>6 months; 4. Age=18; 5. No radiation history; 6.No severe complications, such as hypertension, coronary heart disease or mental illness, no history of severe allergies. 7. HGB=90 g/L,WBC=3.0×10^9/L,ANC=1.5×10^9/L,PLT=50×10^9/L,SCr=1.5 ×ULN,TBIL=1.5×ULN, AST and ALT=1.5×ULN; 8. Subjects were willing to join in this study and sign the informed consent.
Exclusion criteria
Exclusion criteria: Patients with any of the following may not be included in this study: 1. The patient has (a history of) other malignant tumors, but has been cured except cervical carcinoma in situ,non melanoma skin cancer and superficial bladder tumor in the past five years; 2. Pregnant or lactating patients; 3. 4 weeks prior to the start of the study involved in other clinical trial; 4. A history of immune deficiency, or has other acquired, congenital immunodeficiency disease, or a history of organ transplantation; 5. According to the researcher's judgment, there are serious diseases that endanger the patient's safety or influence the clinical research; 6. The time from the first chest radiotherapy to the first chemotherapy was more than 60 days; 7. The researchers asked for the quitting of enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thoracic local control rate;Thoracic PFS;PFS; | — |
Secondary
| Measure | Time frame |
|---|---|
| OS;Incidence of radiation pneumonia;Incidence of radiation esophagitis; | — |
Countries
China
Contacts
Public ContactLihua Dong
The First Hospital of Jilin University
Outcome results
None listed