Skip to content

The exploration on the intervention of DNP to NPS

The exploration on the intervention of donepezil to the Neuropsychiatric symptoms of patients with Alzheimer's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800018064
Enrollment
Unknown
Registered
2018-08-28
Start date
2019-01-01
Completion date
Unknown
Last updated
2018-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mild cognitive impairment

Interventions

Two groups:donepezil versus blank

Sponsors

Shanghai Jiao Tong University affiliated sixth People's hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Han Chinese; 2. MCI stage, MMSE score 24 to 27 and MoCA score < 26; 3. using donepezil (2.5-10mg daily).

Exclusion criteria

Exclusion criteria: 1. not Alzheimer's disease; 2. using other drus metabolized by CYP2D6; 3. With other severe heart, brain, liver and kidney diseases.

Design outcomes

Primary

MeasureTime frame
concentration of 5-HT;

Countries

China

Contacts

Public ContactLu Jin

Shanghai Jiao Tong University affiliated sixth People's hospital

lujinsysu@hotmail.com+86 15026990219

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026