mild cognitive impairment
Conditions
Interventions
Two groups:donepezil versus blank
Sponsors
Shanghai Jiao Tong University affiliated sixth People's hospital
Eligibility
Sex/Gender
All
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Han Chinese; 2. MCI stage, MMSE score 24 to 27 and MoCA score < 26; 3. using donepezil (2.5-10mg daily).
Exclusion criteria
Exclusion criteria: 1. not Alzheimer's disease; 2. using other drus metabolized by CYP2D6; 3. With other severe heart, brain, liver and kidney diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| concentration of 5-HT; | — |
Countries
China
Contacts
Public ContactLu Jin
Shanghai Jiao Tong University affiliated sixth People's hospital
Outcome results
None listed