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Umbilical Cord Patch Transplantation for Corneal Perforations and Descemetoceles

Umbilical Cord Patch Transplantation for Corneal Perforations and Descemetoceles

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800018039
Enrollment
Unknown
Registered
2018-08-28
Start date
2017-03-01
Completion date
Unknown
Last updated
2018-09-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Corneal Perforations and Descemetoceles

Interventions

Sponsors

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Age between 18 and 75 years male and female; 2. Patients diagnosed with deep corneal ulcer, including corneal perforation, post-elastic layer bulging, etc.; 3. The patient agrees to participate in the test, cooperate with treatment and follow-up, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Superficial corneal ulcer, which does not endanger patients with rupture and perforation of eyeball; 2. Severe allergic constitution; 3. Women during pregnancy or lactation; 4. Serious heart, liver, kidney and other organ diseases;Such as cardiac insufficiency ? magnitude (including ? level), hepatic function (ALT, AST) more than 2 times higher than normal ceiling, creatinine (Cr) exceeds the upper limit of normal); More than 5, hypertension II period (including II period, 160-179 or 100-109 mmHg for hypertension II); 6. Severe diabetes (fasting blood glucose is still greater than 8mmol/L after taking blood glucose control measures); 7. Hypoproteinemia; 8. Suffering from mental illness; 9. The investigator considers it inappropriate to participate in this clinical trial.

Design outcomes

Primary

MeasureTime frame
corneal thickness;fluorescent staining;

Countries

China

Contacts

Public ContactZhang Mingchang

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

13871226220@163.com+86 13871226220

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026