Cirrhosis with portal hypertension
Conditions
Interventions
Sponsors
Shanghai Public Health Clinical Center
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Clinically confirmed hepatitis B cirrhosis patients with advanced portal hypertension; 2. Abdominal enhanced CT or magnetic resonance imaging suggest that the left / right primary branches of intrahepatic portal vein can construct shunt; 3. Previous endoscopic history of bleeding from ruptured esophagogastric varices and subsequent rebleeding after standard grade 2 prophylaxis; 4. Liver function was Child A/B grade, ALT/AST < 5 times normal upper limit, total bilirubin < 51umol/L; 5. Prothrombin time does not exceed the upper limit of 3 seconds.
Exclusion criteria
Exclusion criteria: 1. a history of liver surgery or intervention; 2. Massive or diffuse liver masses; 3. Biliary obstruction or portal vein embolism; 4. Pulmonary artery pressure > 40 mmHg, left ventricular ejection fraction < 50%, congestive heart failure or severe valve insufficiency; 5. People with contraindications to MRI examination; 6. Unable to sign informed consent due to physical and mental abnormality.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T1 relaxation time; | — |
Countries
China
Contacts
Public ContactYuan Min
Shanghai Public Health Clinical Center
Outcome results
None listed