Diabeitc nephropathy
Conditions
Interventions
Group 2:Basic treatment of hypoglycemic medicine, hypotensive medicine and dietary treatment plus irbesartan
Group 1:Basic treatment of hypoglycemic medicine, hypotensive medicine and dietary treatment plus TCM treatment based on syndrome differentiation
Sponsors
Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Serum creatinine (Scr) was stable below 265umol/L for 3 months; 2. The diastolic blood pressure was kept stable below 90mmHg after hypotension, the blood glucose was basically controlled, and the glycosylated hemoglobin (HbA1c) was controlled below 7%; 3. TCM syndrome differentiation is Yin deficiency type (including manifestations of Yin deficiency and Qi deficiency), or Yang deficiency type (including manifestations of Yang deficiency and Qi deficiency), or Yin and Yang deficiency type (including manifestations of Yin deficiency, Yang deficiency and Qi deficiency), or blood stasis obstructing collateral vessel type, or dampness turbidity type.
Exclusion criteria
Exclusion criteria: 1. Intractable edema; 2. Urine protein > 10g/24h, serum albumin < 25g/L; 3. renovascular hypertension; 4. Patients have emergency and severe cases within 6 months, which like malignant hypertension, myocardial infarction, cerebrovascular accident, diabetic ketoacidosis and so on; 5. Combination with congestive heart failure of level I-IV; 6. Patients who are not suitable for this intervention, such as patients with cancer, pregnancy and patients being allergic to intervening drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| endpoint event; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24h urinal protein;urinary albumin excretion rate;serum creatinine;Glomerular filtration rate;Scores of TCM syndromes;Scores of QOL; | — |
Countries
China
Contacts
Public ContactJinxi Zhao
Dongzhimen Hospital affiliated to Beijing University of Chinese Medicine
Outcome results
None listed