neonatal sepsis
Conditions
Interventions
Case series:CRRT treatment
Sponsors
Shanghai Children's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) According to the 2016 international guidelines for the management of sepsis and septic shock, the organ dysfunction that causes host reaction disorder and leads to life-threatening organ dysfunction due to infection is diagnosed as sepsis in neonates, and the diagnosis of neonatal sepsis should be made within 3 days; (2) Children with acute renal injury (AKI) stage 1-2; (3) Age 0-28 days.
Exclusion criteria
Exclusion criteria: (1) Those with severe intracranial hemorrhage or inability to recover from cerebral dysfunction; (2) Patients with complex congenital heart disease; (3) Patients with biofilm allergy; (4) Severe bleeding tendency, platelet 3.0.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| renal function indexes(BUN, Cr);Main inflammatory cytokines (TNFa, il-6, il-10);Changes in blood electrolytes (Na+, K+, Ca2+, Mg2+); | — |
Secondary
| Measure | Time frame |
|---|---|
| Indicators of coagulation function;Blood routine and PCT; | — |
Contacts
Public ContactCheng Cai
Shanghai Children's Hospital
Outcome results
None listed