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Clinical Study on Efficacy of Acupuncture and Its Regulation on NLRP3 Inflammatory in Dry Eye Syndrome Patients

Clinical Study on Efficacy of Acupuncture and Its Regulation on NLRP3 Inflammatory in Dry Eye Syndrome Patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017962
Enrollment
Unknown
Registered
2018-08-24
Start date
2018-08-27
Completion date
Unknown
Last updated
2018-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dry Eye Syndrome

Interventions

Group 1:Electroacupuncutre
Group 2:Warm acupuncture

Sponsors

Shanghai Research Institute of Acupuncture and Meridian
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Meeting the diagnosis criteria of DES; 2. Aged 18~65 years; 3. Volunteer participant with fine compliance and having signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Presence of other eye diseases; 2. Active lesion or recent ophthalmic surgery (3 months); 3. Oral or external application of other drugs for the eye disease; 4. Women in pregnancy and lactation; 5. Presence of severe systemic disease in cardiovascular system, cerebrovascular system, liver, kidney and hematopoietic system.

Design outcomes

Primary

MeasureTime frame
Ocular surface disease index;Break up time;Schimer test I;Fluorescent staining;Meibomian gland loss rate;SF-36 scale of life quality;HAD scale of anxiety and depression;NLRP3 inflammasome;caspase-1;IL-1ß;IL-18;—

Countries

China

Contacts

Public ContactJie Liu

Shanghai Research Institute of Acupuncture and Meridian

yokihilo@qq.com+86 13918816696

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026