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Clinical evaluation of minimal residual disease precise diagnosis by molecular pathology in children with neuroblastoma

Clinical evaluation of minimal residual disease precise diagnosis by molecular pathology in children with neuroblastoma

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017940
Enrollment
Unknown
Registered
2018-08-23
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-08-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Neuroblastoma

Interventions

Gold Standard:Diagnostic criteria for high-risk NB: children aged over 12 months with MYCN gene amplification or older than 18 months,clinical stage IV NB.
Index test:MYCN,&#32
BPTF,&#32
PHOX2B

Sponsors

Beijing Children's Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 18 Years

Inclusion criteria

Inclusion criteria: Meet the diagnostic criteria for high-risk NB; Younger than 18 years of age; Patients who have not started treatment before the first diagnosis of NB; Voluntarily sign informed consent; admit to the professional ward of our center and received high risk standardized NB treatment

Exclusion criteria

Exclusion criteria: Patients with serious complications who could not participate in the study; Patients with poor compliance to treatment or clinical studies; A patient whose treatment is discontinued or followed up after a non-medical event occurs during the course of treatment

Design outcomes

Primary

MeasureTime frame
MYCN;plasma DNA;BPTF;PHOX2B;

Countries

China

Contacts

Public ContactXiao Li Ma

Beijing Children's Hospital, Capital Medical University

mxl1123@vip.sina.com+86 13370115038

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026