Acute Cerebral Infarction
Conditions
Interventions
CEGI group:All patients were given standard care once daily for 14 days, including oral 200g aspirin enteric-coated tablet and 20 mg atorvastatin calcium, and intravenous infusion of 250~500 ml 0.9% s
Placebo group:All patients were given standard care once daily for 14 days, including oral 200g aspirin enteric-coated tablet and 20 mg atorvastatin calcium, and intravenous infusion of 250~500 ml 0.9
Sponsors
Peking University Third Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. those diagnosed with first-ever acute cerebral infarction within 48 hours of onset or relapsed ischemic stroke with a score of 0-1 on modified Rankin Scale (mRS); 2. aged between 18 and 75 years old; 3. had a score of 5-22 points on the National Institutes of Health Stroke Scale (NIHSS); and (d) signed informed consent form.
Exclusion criteria
Exclusion criteria: 1. they were diagnosed with transient ischemic attack (TIA), non-responsible multi lacunar infarction, cerebral hemorrhage after infarction, subarachnoid hemorrhage, and/or post-circulation ischemia; 2. had hemiplegia caused by brain tumor, brain injury, brain parasitic diseases and metabolic disorder, cerebral embolism caused by rheumatic heart disease, coronary heart disease, or other heart disease with atrial fibrillation; 3. had gangliosidoses (such as Familial Mongolian idiocy); 4. thrombolytic patients or peptic ulcer patients who cannot take aspirin; 5. had severe primary disease of cardiovascular, liver (ALT or AST exceeding a 1.5-fold upper range value), renal (blood urea nitrogen (BUN) exceeding a 1.2-fold upper range value , creatinine exceeding a 2-fold upper range value), hematopoietic, and/or endocrine system; 6. presented allergies to the study drug or protein; 7. depended on drug or alcohol; 8. pregnant or lactating women; 9. participated in other clinical trials within the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mRS on day 90; | — |
Secondary
| Measure | Time frame |
|---|---|
| NIHSS;Barthel Index scores; | — |
Countries
China
Contacts
Public ContactZhang Hui
Peking University Third Hospital
Outcome results
None listed