Persistent inflammation, immunosuppression,catabolism syndrome
Conditions
Interventions
Case series:Probiotics
Sponsors
Ruijin Hospital North Compus, Shanghai Jiaotong University, Medical School
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 80 years; 2. According to the diagnostic criteria of PICS: ICU stay > 10 days, inflammation index: CRP > 150 Hg/dl, retinol binding protein concentration < 1 mg/dL, immunosuppressive state: lymphocyte count < 0.8 * 10^9/L, high catabolism state: plasma albumin level < 3.0 g/dl, creatinine height index < 80%, weight loss 10%. Or BMI<18 during the whole hospitalization.
Exclusion criteria
Exclusion criteria: 1. hormone or immunosuppressive agents used in the past month; 2. chronic diseases such as tumors;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality;Immunity function; | — |
Countries
China
Contacts
Public ContactLiu Jiao
Ruijin Hospital North Compus, Shanghai Jiaotong University, Medical School
Outcome results
None listed