Chronic Hepatitis B
Conditions
Interventions
observation group:Granules of Chinese Herb
control group:Placebo
Sponsors
Shuguang Hospital affiliated with Shanghai University of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Referring to the diagnostic criteria of CHB in the guidelines for the prevention and treatment of chronic hepatitis B published in 2015 and the diagnostic standard of NAFLD in the guide for the diagnosis and treatment of non-alcoholic fatty liver disease in 2010, the diagnostic criteria for Shi Re Pattern in 2002 "guidelines for clinical research of new drugs of traditional Chinese medicine" and the criteria for the diagnosis and diagnosis of the related documents: 1. Aged 18-60 years old male and female; 2. the elevation of serum alanine aminotransferase (ALT) and total bilirubin (Tbil) in patients with CHB diagnostic criteria was 2 times lower than the upper limit of the normal value; the elevation of serum alanine aminotransferase (ALT) or gamma glutamyl phthalase (gamma -GT) in patients with NAFLD diagnostic criteria was 2 times lower than the upper limit of the normal value; (1) Shi Re Pattern group: it accords with disease diagnosis standard and TCM damp heat syndrome standard; (2) Latent Pattern group: only meet the diagnostic criteria of disease, not meet the criteria of damp-heat syndrome and other syndromes of traditional Chinese medicine, no obvious clinical symptoms and signs; 3. normal control group: choose healthy volunteers with gender and age matched with case group; 4. I or guardian agreed to participate in the clinical trial control study and signed informed consent.
Exclusion criteria
Exclusion criteria: (1) patients complicated with other hepatitis or severe hepatitis; (2) severe heart, liver, hematopoietic, nervous system complications and drug allergy; (3) malignant tumors, connective tissue diseases; (4) pregnant or lactating women; cases with other important diseases; (5) mental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| metabolic substance; | — |
Secondary
| Measure | Time frame |
|---|---|
| liver function;kidney function;blood test; | — |
Countries
China
Contacts
Public ContactZhang Hua
Shuguang Hospital affiliated with Shanghai University of TCM
Outcome results
None listed