glaucoma
Conditions
Interventions
Gold Standard:Suspected glaucoma group inclusion criteria:
(1) Intraocular pressure value = 22 mm Hg (three consecutive measurements without any treatment)
(2) large nipple depression, C/D = 0.6, combined or bilateral difference = 0.2
At least two reliable (false negative rate <15%, false positive rate <15%, fixation loss <20%)
Index test:Optic 
density, 
blood 
GCIPL 
thickness,Visual 
(MD), 
(PSD), 
Sponsors
Department of Ophthalmology, Zhongnan Hospital of Wuhan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Suspected glaucoma group inclusion criteria: 1. Intraocular pressure value = 22 mm Hg (three consecutive measurements without any treatment); 2. large nipple depression, C/D = 0.6, combined or bilateral difference = 0.2; 3. At least two reliable (false negative rate 95%); 4. Average RNFL thickness = 95% confidence interval; Satisfy (3) and (4) and satisfy at least one of (1) and (2). The normal control group included the criteria: 1. Both intraocular pressures are 95%); 4. average RNFL thickness = 95% confidence interval; 5. normal fundus examination, no other eye disease except refractive error. Inclusion criteria for glaucoma: According to the consensus of experts on diagnosis and treatment of primary glaucoma in China (2014).
Exclusion criteria
Exclusion criteria: 1. Aged 80 years; 2. Best corrected visual acuity +3.0D; 3. History of internal eye surgery (except glaucoma surgery or non-complex cataract surgery); 4. secondary glaucoma and non-glaucoma optic neuropathy; 5. other ocular or systemic diseases that affect the visual field; 6. vascular or non-vascular retinopathy; 7. can not be matched with visual field examination Subjects with reliable parameters; 8. Refractive interstitial opacity affecting blood flow signals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Optic disc vascular density;Optic disc blood perfusion density;GCIPL thickness;Visual field average defect (MD);mode standard deviation (PSD);visual field index; | — |
Countries
China
Contacts
Public ContactKe Min
Department of Ophthalmology, Zhongnan Hospital of Wuhan University
Outcome results
None listed