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Effect of individualized blood pressure management on the outcome of patients at high-risk major surgery: a randomized controlled trial

Effect of individualized blood pressure management on the outcome of patients at high-risk major surgery: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017786
Enrollment
Unknown
Registered
2018-08-14
Start date
2018-09-01
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complication of anesthesia

Interventions

Control:Target blood pressure with SBP <80 mmHg, MAP<60mmHg or 40% lower than baseline
Treatment:Taking the average blood pressure during sleep as the target blood pressure

Sponsors

The Second Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Older than 65 years old; 2. ASA is larger than grade II; 3. Non cardiac and non Department of neurosurgery operations with operation time greater than 2 hours.

Exclusion criteria

Exclusion criteria: 1. Severe preoperative hypertension (uncontrolled); 2. Creatinine clearance rate <30 ml / min or preoperative dialysis; 3. Acute heart failure; 4. Preoperative septicemia; 5. Preoperative hemodynamic failure (shock); 6. Intraoperative spinal anesthesia.

Design outcomes

Primary

MeasureTime frame
Postoperative systemic inflammatory response syndrome or heart, brain, and kidney dysfunction;—

Countries

China

Contacts

Public ContactLi Rui

The Second Hospital of Anhui Medical University

lrayd@sina.com+86 13855114159

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026