Hypertension
Conditions
Interventions
Case series:Radio Frequency Renal denervation
Sponsors
Southeast University affiliated Zhongda Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Ages of 18 to 75, male or female; 2. Main renal artery, with or without accessary renal arteries, with length =20mm; 3. Patients who have not taken any anti-hypertensive drugs or have been off drugs for at least 2 weeks, with mean SBP =150mmHg and =180mmHg based on at least 3 office blood pressure measurements, or ASBP=135mmHg and =170mmHg based on 24 hr blood pressure monitoring; 4. Agrees to take part in the trial and signs the written, informed consent.
Exclusion criteria
Exclusion criteria: 1. Renal artery abnormalities that are inappropriate for the procedure; 2. Pregnant or plan to become pregnant; 3. History of orthostatic hypotension; 4. Type I diabetes; 5. Estimated GFR<40mL/min/1.73m2; 6. Only one kidney or prior kidney transplantation; 7. Bleeding tendency or other coagulation related diseases; 8. Acute or severe systemic infection; 9. Prior renal artery interventional procedures or prior RDN treatment; 10. History of stroke or TIA; 11. Malignant tumor or end-stage illnesses; 12. Secondary hypertension; 13. Acute coronary events within 2 weeks; 14. Other conditions that deem unsuitable for the procedure, in the opinions of investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood Pressure; | — |
Countries
China
Contacts
Public ContactMa Gen-Shan
Southeast University affiliated Zhongda Hospital
Outcome results
None listed