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Effect of Pirfenidone gel on urethral stricture recurrence after internal urethrotomy

Effect of Pirfenidone gel on urethral stricture recurrence after internal urethrotomy

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017742
Enrollment
Unknown
Registered
2018-08-12
Start date
2018-08-12
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urethral stricture

Interventions

experiment group:Pirfenidone gel
control group:only receive the surgery for urethral stricture

Sponsors

Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Male adults, Diganosed as urethral stricture, stimate the urethral stricture length < 1.5 cm by the preoperative urinary tract imaging and Urethrocystoscope, sgined the informed consent.

Exclusion criteria

Exclusion criteria: 1. with a history of open urethral surgery or the urethra incision or urethra expansion history for many times; 2. with a history of severe hypertension; 3. with a history of diabetes; 4. with a history of the blood coagulation dysfunction or anticoagulant drugs; 5. with liver or kidney dysfunction; 6. Patients who can not cooperate with treatment; 7. mental disorder or nerve dysfunction.

Design outcomes

Primary

MeasureTime frame
Urinary flow rate;urethrography;

Secondary

MeasureTime frame
routine uronoscopy;

Countries

China

Contacts

Public ContactJihong Wang

Shanghai Jiao Tong University Affiliated Sixth People's Hospital

wangjihong715@sina.com+86 18930170242

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026