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PRP in combination with sodium hyaluronate articular injection in the treatment of knee osteoarthritis short-term effective observation and mechanism research

PRP in combination with sodium hyaluronate articular injection in the treatment of knee osteoarthritis short-term effective observation and mechanism research

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017731
Enrollment
Unknown
Registered
1990-01-01
Start date
2018-08-11
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthtitis

Interventions

Control Group:Platelet Rich Plasma or hyaluronic acid injection
Experimental Group:Platelet Rich Plasma or Platelet Rich Plasma plus hyaluronic acid injection

Sponsors

Guizhou Medical University Affiliated Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. X-ray Kellgren - Lawrence classification belongs to II-III, men and women not limited; 2. nearly 1 month is not taking other drugs or other treatment methods, all the patients can stick to this course.

Exclusion criteria

Exclusion criteria: 1. this drug allergy, taboo or allergic constitution; 2. X-ray classification standard is IV with knee joint replacement surgery indications; 3. secondary osteoarthritis, such as infectious arthritis, rheumatoid arthritis, patients with hemophilia sex arthritis, gouty arthritis, etc; 4. caused by knee joint injury of meniscus, ligament injury and nerve vascular injury patients; 5. a serious disease of heart head blood-vessel, liver and kidney disease, endocrine system disease, blood system diseases and psychiatric patients; 6. Pregnancy and lactation women; 7. knee bad skin condition can't be punctured; 8. Treated with other drugs or methods in the process of end treatment and not completed the course.

Design outcomes

Primary

MeasureTime frame
WOMAC score;lysholm score;Lequesne score;Dynamiic VAS score;

Secondary

MeasureTime frame
VAS score;

Countries

China

Contacts

Public ContactChuan Ye

Guizhou Medical University Affiliated Hospital

545255355@qq.com+86 13984822777

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026