poor ovarian response
Conditions
Interventions
Experiment Group:acupuncture + COH
Control group:COH
Sponsors
Institute of acupuncture and moxibustion, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
Female
Age
35 Years to 40 Years
Inclusion criteria
Inclusion criteria: (1) according to the diagnostic criteria of POR; (2) having IVF or Intracytoplasmic sperm injection (ICSI) for gestational indications; (3) Aged 35 to 40 years old.
Exclusion criteria
Exclusion criteria: (1) patients with recurrent spontaneous abortion more than 2 times (including biochemical abortion); (2) Repeated implantation failure (at least 3-6 high-quality embryos transplanted without clinical pregnancy after at least 3 transplantation cycles); (3) the patients with uterine malformation (single angle uterus, double horned uterus, double uterus, untreated mediastinal uterus) and other patients with endometriosis (adenomyosis, submucous hysteromyoma, intrauterine adhesion and scar uterus); (4) patients and their husbands had abnormal karyotype (excluding chromosome polymorphism); (5) untreated patients with hydrosalpinx; (6) a contraindication of ART and pregnancy, or a patient with a definite influence on pregnancy, such as hypertension, heart disease with clinical symptoms, diabetes, liver disease, kidney disease, severe anemia, venous thrombosis, pulmonary embolism or history of cerebral vascular events, and malignant swelling of the tumor; (7) Ovarian dysfunction caused by iatrogenic factors (such as pelvic surgery, radiotherapy and chemotherapy, uterine artery embolism, drugs such as hormones, immunosuppressants, etc.); (8) refusing to sign a letter of informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of retrieved oocytes; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fertilization rate;Cleavage rate;embryo implantation rate;Utilization of embryo rate;embryo implantation rate;Cycle pregnancy r;Antral follicle count;AMH;AMH;Basal hormone level;Menstrual condition;Self-RatingAnxietyScale; | — |
Countries
China
Contacts
Public ContactYigong Fang
Institute of acupuncture and moxibustion, China Academy of Chinese Medical Sciences
Outcome results
None listed