Total knee arthroplasty
Conditions
Interventions
IPM Group:Improved Perioperative Management modal
TPM Group:Traditional Perioperative Management modal
Sponsors
West China School of Medicine, West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with initial unilateral total knee arthroplasty for end-stage osteoarthritis
Exclusion criteria
Exclusion criteria: 1. History of surgical knee surgery, preoperative knee flexion deformity =30 degree, internal and external valgus deformity =30 degree; 2. tranexamic acid use contraindicated patients (six months of thrombosis-related events); 3. surgical side limb neuropathy; 4. alcohol abuse patients, long-term use of opioid patients (defined as patients who use opioids almost every day longer than March); 5. preoperative hemoglobin (Hb) 35 or <20, age less than 18 or 80 years old, American Society of Anesthesiologists (ASA) 4 or 5 patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS Score at rest and Activity;time to active straight leg raising;time up and go test;10 meters walk test;30 s chair test;Range of motion;Time for staircase competency;Postoperative length hospital stay;Patient satisfaction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Total blood loss and invisible blood loss;swelling ratio;Infusion volume on the day of surgery;CRP?IL-6;Hypoproteinemia and electrolyte disorders;Number of postoperative wound-related complications;Incidence of deep vein thrombosis;Pulmonary aspiration, aspiration pneumonia persons; | — |
Countries
China
Contacts
Public ContactGuanglin Wang
West China School of Medicine, West China Hospital, Sichuan University
Outcome results
None listed