Skip to content

Identification of susceptibility genes for postoperative cognitive dysfunction and its mechanism

Identification of susceptibility genes for postoperative cognitive dysfunction and its mechanism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017632
Enrollment
Unknown
Registered
2018-08-07
Start date
2018-09-01
Completion date
Unknown
Last updated
2024-05-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitive dysfunction

Interventions

POCD group (preliminary screening):None
Non-POCD group (preliminary screening):None
POCD group (Further verification):None
Non-POCD group (Further verification):None

Sponsors

First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
40 Years to 75 Years

Inclusion criteria

Inclusion criteria: Aged 40-75 years, and simple intelligence scale score (MMSE) > 24 points, ASA I-II, patient will be undergoing elective general anesthesia on the downward abdominal surgery.

Exclusion criteria

Exclusion criteria: CT examination eliminate organic brain damage, such as epilepsy, anxiety and depression, psychological system disease or severe body disease, always with encephalopathy, drug dependence, substance abuse, and/or use nearly three months anticonvulsants, sedatives and antidepressants, seeing and hearing disorders, has the long-term insomnia, for other reasons can't visit patients to communicate, to predict possible or happened difficult airway patients

Design outcomes

Primary

MeasureTime frame
genotype;folNeuropsychological low-up result;folNeuropsychological low-up result;

Countries

China

Contacts

Public ContactGuanghong Xu

First Affiliated Hospital of Anhui Medical University

xuguanghong2004@163.com+86 13856949535

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026