Thrombotic diseases
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) Male and female aged =18 years; (2) only using clopidogrel for more than 3 days; (3) Chinese Han population; (4) The patients or their families agree to voluntarily participate in this study and sign informed consent.
Exclusion criteria
Exclusion criteria: (1) patients with severe liver and renal insufficiency; (2) patients with severe digestive ulcer; (3) patients with malignant tumors; (4) patients with allergy or intolerance to clopidogrel; (5)patients received anticoagulant antiplatelet or thrombolytic therapy in one months; (6) poor compliance, unable to cooperate with the treatment; (7) patients with severe abnormal platelet function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Maximum aggregation rate of platelets (MAR);Related genotype; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of primitive platelets;Mean volume of primitive platelets;Average aggregation rate of platelets;The maximum platelet aggregation time; | — |
Countries
China
Contacts
Henan Provincial People's Hospital, Zhengzhou University People's Hospital