diabetic foot ulcers
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients were considered for inclusion in the study if they had a history of diabetes mellitus, and nonhealing or recurrent ulcer(s) at the lower limb. A nonhealing ulcer was defined as the failure of an ulcer to heal with conservative and/or surgical treatments.
Exclusion criteria
Exclusion criteria: 1) not able to tolerant the anesthesia required for the surgery; 2) with clinical history of stroke, cardiac failure, cancer, or renal failure (as suggested by creatinine higher than 177 µmol/l); 3) with local signs of infection presented as cellulitis or suppuration at the surgical site or malignant disease in the wound; 4) patients who were not diabetic; 5) with active Charcot arthropathy of the foot; 6) being treated with corticosteroids, immunosuppressive drugs, or chemotherapy; 7) with neurological problem complicating the rehabilitation; 8) with severe peripheral vascular disease (with popliteal artery with occlusion more than 85% lumen); 9) with history of mental disorder interfering with patient compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rates of ulcer healing, time to heal, recurrence rate, and proportion of amputation; | — |
Countries
China
Contacts
The First Affiliated Hospital of Guangxi Medical University