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Effect of sarcopenia on that acute toxicity of radiotherapy and chemotherapy for nasopharyngeal carcinoma

Effect of sarcopenia on that acute toxicity of radiotherapy and chemotherapy for nasopharyngeal carcinoma: a prospective cohort study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017539
Enrollment
Unknown
Registered
2018-08-03
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nasopharyngeal carcinoma

Interventions

Case series:None

Sponsors

Affiliated Tumor Hospital of Guangxi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Any age, gender and tumor stage; 2. confirmed by the department of pathology of our center as the primary treatment and no metastasis of nasopharyngeal carcinoma; 3. patients with severe heart, liver and kidney dysfunction are excluded; 4. the treatment methods include simple radiotherapy, synchronous chemo-radiotherapy, neoadjuvant chemotherapy plus synchronous chemo-radiotherapy, and targeted therapy for the above treatment, and the whole treatment is completed; 5. high quality abdominal CT images can be used for skeletal muscle analysis; 6. the motor function of lower limbs has no obstacle to daily activities; 7. no neurological diseases, mental disorders, normal communication.

Exclusion criteria

Exclusion criteria: 1. Patient diagnosed with recurrent or metastatic nasopharyngeal carcinoma; 2. patient with unclear tumor stages (such as liver, lung, bone and other suspected metastases to be determined); 3. incomplete chemoradiotherapy; 4. severely impaired heart, liver and kidney function; 5. no abdominal CT examination was performed before or after treatment.

Design outcomes

Primary

MeasureTime frame
Skeletal muscle Index;handgrip strength;6 m walking speed;

Secondary

MeasureTime frame
waist circumference;weight;Total lymphocyte count;albumin, ALB;triglyceride, TG;Blood sugar;High-density lipoprotein cholesterol,HDL-C;uric acid, UA;blood pressure;

Countries

China

Contacts

Public ContactXiaodong Zhu

Affiliated Tumor Hospital of Guangxi Medical University

zhuxiaodong83@163.com+86 13978873616

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026