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Anti-scarring study after glaucoma surgery

Effect of cyclosporine A and conbercept on the prognosis of trabeculectomy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017532
Enrollment
Unknown
Registered
2018-08-02
Start date
2018-01-01
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

glaucoma

Interventions

Group A:Cyclosporine A eye drops 3 days before and 3months after glaucoma surgery
Group 2:Subconjunctiva injection of conbercept during glaucoma surgery

Sponsors

Eye and ENT Hospital of Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Primary open angle glaucoma and primary angle closure glaucoma patients; 2. Age older than 18 years; 3. IOP higher than 21 mmHg, medically uncontrolled and surgery needed; 4. Glaucomatous optic nerve damage: larger cup to disc ratio,narrower rim and thinner retinal nerve fiber layer; 5. Damaged visual field; 6. Consented to attend the study.

Exclusion criteria

Exclusion criteria: 1. Past history of ocular surgery or trauma; 2. Other ocular diseases such as uveitis or infection; 3. Obvious eye irritation synptoms; 4. Fundus changes secondary to diabetes of hypertension; 5. System medications which might damage optic nerve; 6. Pregnant or breastfeeding women.

Design outcomes

Primary

MeasureTime frame
Intraocular pressure;

Secondary

MeasureTime frame
Anterior segment photograph;Height of blebs;Area of blebs;

Countries

China

Contacts

Public ContactKong Xiangmei

Eye and ENT Hospital of Fudan University

kongxm95@163.com+86 13817890921

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026