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Preventive transcatheter arterial chemoembolization (TACE) after hepatectomy: a Prospective, open label and randomized controlled trial

Preventive transcatheter arterial chemoembolization (TACE) after hepatectomy: a prospective, open label and randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017517
Enrollment
Unknown
Registered
2018-08-02
Start date
2018-08-01
Completion date
Unknown
Last updated
2020-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resectable liver cancer

Interventions

Experimental group:c-TACE

Sponsors

The First Affiliated Hospital Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. strictly conforms to the standard of clinical diagnosis of the diagnosis and treatment of primary liver cancer (2017 Edition), which is clinically diagnosed as primary liver cancer and received radical resection of liver cancer. 2. patients with primary hepatocellular carcinoma confirmed by histopathology or cytological examination after operation. 3. age: more than 18 years old, not limited to men and women; 4. ECOG score was 0-2 points, and the estimated survival time was 3 months; 5. Child-Pugh liver function rating: A or better B level (less than 7 points); 6. the main organs are functioning normally, that is, they meet the following criteria: (1) blood routine examination: (no blood transfusion, no use of G-CSF, no medication correction) within 14 days before the screening: 1) HB > 90 g/L; 2) WBC > 1.5 x 10^9/L; 3) PLT > 50 x 10^9/L; (2) biochemical examination: (not lost ALB within 14 days); 1) ALT and AST ULN; 3) creatinine was less than 1.5 of ULN; 7. the volunteers voluntarily joined the study, signed informed consent, and had good compliance and follow-up.

Exclusion criteria

Exclusion criteria: 1. pregnant or lactating women or fertile patients are unwilling or unable to take effective contraceptive measures. 2. Previous or concurrent cases of other untreated malignancies, with the exception of cured basal cell carcinoma of the skin, carcinoma in situ of the cervix and superficial bladder cancer; 3. patients who had previously undergone liver transplantation; 4. patients with HIV infection; 5. patients with incomplete clinical and pathological data before operation; 6. preoperative pathological features of distant metastasis patients; 7. patients receiving other antitumor drugs (including molecular targeted therapy, systemic chemotherapy, etc.); 8. the researchers judged other situations that might affect clinical research and determine the results of the study.

Design outcomes

Primary

MeasureTime frame
1 year tumor recurrence rate;

Secondary

MeasureTime frame
survival rate;

Countries

China

Contacts

Public ContactJun-hui Sun

The First Affiliated Hospital Zhejiang University

yuelin002@126.com+86 13575725162

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026