chronic heart failure
Conditions
Interventions
chronic heart failure:Qi-tonifying formula
Normal control:none
Sponsors
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 35-75 years old, male or female; 2. TCM diagnosis of Qi-deficiency syndrome or Qi-deficiency and Blood-stasis syndrome; 3. Meeting the diagnostic criteria of both chronic heart failures and coronary heart diseases; 4. Patients with class II-III of NYHA; 5. Left ventricular ejection fraction (LVEF) = 40%; 6. Volunteers participate with signed the Letter of Informed and Consent.
Exclusion criteria
Exclusion criteria: 1. Patients with one of the following conditions: acute coronary syndrome within 30 days; cardiogenic shock; second degree Morbiz II sinoatrial or atrioventricular block without pacemaker implantation therapy, uncontrolled malignant arrhythmias; dilated cardiomyopathy; hypertrophic obstructive cardiomyopathy; myocarditis; pulmonary embolism; severe valvular disease; stroke in recent 6 months; 2. Patients with severe liver and kidney function damage, with alanine aminotransferase> 3 times of the upper limit of normal, or serum creatinine> 265umol/L; 3. Patients with major systemic diseases combined such as the respiratory system, nervous system, and immune system, patients with malignant tumors or with severe trauma or infection; 4. Poorly controlled chronic diseases such as hypertension and diabetes; 5. Those who have complicated accompanying syndromes, including excess syndromes such as phlegm, coldness, and heat toxicity, as well as patients with obvious Yin-deficiency or Yang-deficiency; 6. Patients with allergic constitution; 7. Women who are pregnant, lactating, or have a pregnancy intention or positive pregnancy test (test urine HCG or blood HCG), or those who cannot take effective contraception during the study (effective contraception includes sterilization, IUD, oral contraceptives or the diaphragm method by the local law); 8. Patients who participated in other drug clinical trials in the past 1 month; 9. Patients with mental disorders, neurological impediments, or failure to express themselves or communicate; 10. Alcoholics, drug abusers and addicts.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The syndrome scorings of the Qi-deficiency; | — |
Secondary
| Measure | Time frame |
|---|---|
| LVEF;NT-BNP; | — |
Countries
China
Contacts
Public ContactHao Xu
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Outcome results
None listed