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Single Center, Open and Prospective Evaluation of Genomic Sequencing on Cerebro-Spinal Fluid, brain metastatic lesions andperipheral blood from patients in non-small cell lung cancer with brain metastasis

Single Center, Open and Prospective Evaluation of Genomic Sequencing on Cerebro-Spinal Fluid, brain metastatic lesions andperipheral blood from patients in non-small cell lung cancer with brain metastasis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017499
Enrollment
Unknown
Registered
2018-08-02
Start date
2018-08-03
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

non-small cell lung cancer with brain metastasis

Interventions

Gold Standard:brain metastatic lesions sample
Index test:Cerebro-Spinal&#32
Fluid,&#32
and&#32
peripheral&#32
blood

Sponsors

Tianjin Huanhu Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years male and female, estimated survival time=2 mouths; 2. confirmed advanced NSCLC with brain metastases by pathologically; 3. MRI indicated that the measurable brain metastasis lesion.

Exclusion criteria

Exclusion criteria: 1. Blood or CFS is not available; 2. Pregnant or lactating female patient; 3. have ever used AZD-9291 (TAGRISSO).

Design outcomes

Primary

MeasureTime frame
Gene mutation;SEN, SPE, ACC;

Countries

China

Contacts

Public ContactRong Jiang

Tianjin Huanhu Hospital

jiangrong1989@sina.com+86 15902296269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 21, 2026