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Effects of intravenous administration of lidocaine and dexmetomidine on the inhibition of cough during extubation in patients with thyroid surgery - randomized, double-blind, controlled trial

Effects of intravenous administration of lidocaine and dexmetomidine on the inhibition of cough during extubation in patients with thyroid surgery - randomized, double-blind, controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017482
Enrollment
Unknown
Registered
2018-08-01
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid tumor

Interventions

L group:Intravenous administration of lidocaine
D group:Intravenous administration of dexmetomidine

Sponsors

Anqing hospital affiliated to Anhui Medical university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) patients with thyroid benign tumor were identified before surgery; (2) sign a written consent to know the circumstances; (3) normal cardiopulmonary function; (4) aged from 18 to 65 years; (5) ASA I-II.

Exclusion criteria

Exclusion criteria: (1) asthma; (2) chronic cough; (3) I had an upper respiratory infection two weeks ago; (4) taking angiotensin-converting enzyme inhibitors, bronchodilators or steroids; (5) sinus bradycardia and atrioventricular block; (6) hepatic and renal insufficiency; (7) local anaesthesia allergy.

Design outcomes

Primary

MeasureTime frame
Cough;—

Secondary

MeasureTime frame
Postoperative drainage;—

Countries

China

Contacts

Public ContactWang Shengbin

Anqing hospital affiliated to Anhui Medical University

aqslyywsb@163.com+86 13955665151

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 3, 2026