Gynecologic surgery patients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: (1) young people aged 18-45 years old; (2) the subjects must have informed consent before the trial and voluntarily sign the written informed consent; (3) subjects were able to communicate well with researchers and complete research in accordance with research requirements.
Exclusion criteria
Exclusion criteria: (1) abnormal liver and kidney function (AST, ALT above 2 times normal upper limit; Scr normal upper limit 1.2 times higher); (2) compensated circulatory disorder (severe hypotension), grade II-III atrioventricular block, severe cardiovascular disease, and endocrine system diseases; (3) taking alpha 2 agonist or antagonist (such as clonidine) within 14 days before operation, taking anticonvulsant or cardiovascular active drugs before operation; (4) any drug that inhibits or induces the metabolism of the liver during the first 30 days of the trial (such as the inducer - barbiturate, C Masi Bing, phenytoin, glucocorticoid, Omeprazole; inhibitors - SSRI antidepressants, cimetidine, diltiazem, macrocyclic ester, nitroimidazole, sedative hypnotics, and hypnotics) Vera Pammy, fluoroquinolones, antihistamine; (5) blood donation and blood donation >400mL or blood transfusion were taken within 3 months before the test; (6) drug abusers or the use of soft drugs (such as cannabis) within 3 months prior to the trial or a hard drug (such as cocaine, piperidine, etc.) within 1 years before the trial; (7) women in pregnancy or lactation; (8) subjects may not be able to complete the study or other researchers who think they should not be included for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sedation effect; | — |
Countries
China
Contacts
The Third Xiangya Hospital of Central South University