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To study the cytochrome P450 enzymes CYP3A4 SNP (single nucleotide polymorphisms) associated with personalized medicine for labor analgesia

To study the cytochrome P450 enzymes CYP3A4 SNP (single nucleotide polymorphisms) associated with personalized medicine for labor analgesia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017455
Enrollment
Unknown
Registered
2018-07-31
Start date
2018-08-15
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Labor Pain

Interventions

Polymorphism groups:the polymorphism of cytochrome P450 enzyme CYP3A4*1g

Sponsors

Beijing Obsterics and Gynecology Hospital, Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Chinese healthy full-term birth, no alcohol, tobacco, hobby, the experiment purpose, main pharmacological effects of drugs and the possibility of adverse drug reactions, rights and interests of the subjects, such as understanding, willing to take the risk and signed the informed consent.

Exclusion criteria

Exclusion criteria: A motion sickness, liver and kidney disease, gastrointestinal disease, cardiovascular disease, chronic pain patients or application history of analgesic drugs;Within a month before the experiment influence CYP3A enzyme activity of drugs and to eat food affect CYP3A enzyme activity in 24 hours.

Design outcomes

Primary

MeasureTime frame
Fetal heart monitoring abnormal;labor pain;—

Countries

China

Contacts

Public ContactXu Mingjun, Zhang Qinglin

Beijing Obsterics and Gynecology Hospital, Capital Medical University

snake650222@163.com+86 13910964953

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026