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Feasibility study of anti-VEGF instead of intraoperative PRP in proliferative diabetic retinopathy

Feasibility study of anti-VEGF instead of intraoperative PRP in proliferative diabetic retinopathy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017448
Enrollment
Unknown
Registered
2018-07-30
Start date
2019-02-01
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

proliferative diabetic retinopathy

Interventions

Group 1:vitreoretinal surgery combined with whole retina photocoagulation
Group 2:vitreoretinal surgery combined with anti-VEGF therapy

Sponsors

The Eye Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: (1) Age=18 years old; (2) type 1 or type 2 diabetes. (3) proliferative diabetic retinopathy with vitreous hemorrhage, and conservative treatment of vitreous hemorrhage without obvious absorption for 1 month requires vitreoretinal surgery; (4) The postoperative refractive medium is clear and the pupil is large enough to obtain sufficient clear fundus.

Exclusion criteria

Exclusion criteria: (1) Previously received panretinal photocoagulation or unfinished panretinal photocoagulation; (2) Pulling retinal detachment involving the macula or the presence of extensive fiber proliferation requires silicone oil filling; (3) anterior chamber neovascularization or neovascular glaucoma; (4) other vascular diseases such as retinal vein occlusion, arterial occlusion, etc; (5) received intraocular anti-VEGF therapy or triamcinolone acetonide treatment which are still in the treatment period.

Design outcomes

Primary

MeasureTime frame
viusal field;

Secondary

MeasureTime frame
best corrected visual acuity;Electroretinogram;OCT;IOP;

Countries

China

Contacts

Public ContactYong Wei

The Eye Hospital of Wenzhou Medical University

weiyongdoctor@163.com+86 15860759255

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026