Tuberculosis
Conditions
Interventions
experimental group 1 with Non-diabetic TB patients:2HL2 EZS/2HL2EZS3/4HL2E
experimental group 2 with Non-diabetic TB patients:2HL2 EZS/2HL2EZS3/8HL2E
experimental group 3 with Non-diabetic TB patients:6HEZLfx/6HELfx
6 L2EZLfx/6 EL2Lfx
control group with Non-diabetic TB patients:2HREZS/6HRE
control group with diabetic TB patients:2HREZS/6HRE
experimental group with diabetic TB patients:6HEZLfx/6HELfx
Sponsors
Beijing Chest Hospital,Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Sign informed consent; 2. aged between 18 and 65 years; 3. first episode of TB re-treatment and have used second-line anti-TB drugs = 2 months; 4. pulmonary active tuberculosis,sputum smear positive for acid-fast bacilli (AFB) and culture positive for M. tuberculosis; 5. with normal liver and kidney function, as well as normal blood and urine test results; fasting blood glucose control in = 7 mmol/L and with no complications of diabetes for diabetic TB patients.
Exclusion criteria
Exclusion criteria: 1. with active extra-pulmonary tuberculosis(concomitant tuberculous pleurisy is not excluded); 2. Nontuberculous mycobacteria; 3. Allergy to any anti-tuberculosis drug; 4. MDR-TB or XDR-TB; 5. active hepatitis, silicosis, renal dysfunction (urine protein positive> = 1 +, etc.), moderate to severe anemia or hematological diseases, pulmonary heart disease, respiratory failure and heart failure patients, long-term alcohol abuse, Immune diseases, malignancies, metabolic diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| cure rate;treatment completion rate;failure rate;death rate;default rate;relapse rate;Lesions absorption;cavity; | — |
Countries
China
Contacts
Public ContactGao Weiwei
Beijing Chest Hospital, Capital Medical University
Outcome results
None listed