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Tranexamic plus Dexamethasone Reduce Inflammatory Response and Complications in Total Knee Arthroplasty: a Randomized Controlled Trial

Tranexamic plus Dexamethasone Reduce Inflammatory Response and Complications in Total Knee Arthroplasty: a Randomized Controlled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017418
Enrollment
Unknown
Registered
2018-07-29
Start date
2018-07-30
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee arthroplasty

Interventions

A:2g TXA + oral DXM 6mg preoperative
B:2g TXA + iv DXM 5mg
C:2g TXA + Saline

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: patients with TKA

Exclusion criteria

Exclusion criteria: aged 85 years, allergy to the TXA, allergy to the DXM

Design outcomes

Primary

MeasureTime frame
CRP;IL-6;inflammatory;complication;—

Countries

China

Contacts

Public ContactZongke Zhou

West China Hospital, Sichuan University

zongke@126.com+86 13207100126

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026