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The research of the BDNF and the D-serin/total serin level in human serum on the dignosis of postoperative cognitive dysfunction based on precision medcine theory

The research of the BDNF and the D-serin/total serin level in human serum on the dignosis of postoperative cognitive dysfunction based on precision medcine theory

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017415
Enrollment
Unknown
Registered
2018-07-29
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction

Interventions

Gold Standard:Mini-mental state examination
Index test:BDNF&#32
and&#32
serin&#32
in&#32
serum

Sponsors

Department of anesthesiolgy of Tongji hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Elderly patients with limb fracture undergo surgery and anesthesia; 2. Age over 65 years; 3. ASA class I-III; 4. Volunteer signing informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with one (or more) of a series brain disease 2. patients complicated with massive hemorrhage during surgery 3. patients who can not cooperates

Design outcomes

Primary

MeasureTime frame
BDNF and serin in serum;cognitive function;—

Countries

China

Contacts

Public ContactLuo Ailin

Wuhan Tongji Hospital

alluo@tjh.tjmu.edu.cn+86 13507122565

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026