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Effect of intravenous dexmedetomidine injection on comfort in patients non-general anesthesia: a prospective, randomized, double-blind, placebo-controlled trial

Effect of intravenous dexmetomidine injection on the comfort of patients undergoing bromhidrosis resection: a prospective randomized, randomized, double-blind placebo-controlled trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017409
Enrollment
Unknown
Registered
2018-07-28
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bromhidrosis

Interventions

Dexmetomidine group:Intravenous dexmetomidine injection

Sponsors

Ningbo 2nd Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. For patients undergoing elective bromhidrosis resection; 2. Aged 18 to 65 years old male and female; 3. BMI 18 kg/m2 to 30 kg/m2; 4. ASA grade I ~ III; 5. The patient has a full understanding of the purpose and significance of this test, and voluntarily participates in this clinical trial, and signs the informed consent.

Exclusion criteria

Exclusion criteria: 1. Screening is bradycardia (heart rate or less 50 times/min), III degree atrioventricular block (not including the use of pacemaker patients), and other serious arrhythmia history; 2. Patients with mental system diseases (such as schizophrenia, depression, etc.) and cognitive dysfunction;Patients with a history of epilepsy;Past history of abuse of psychotropic and narcotic drugs; 3. Patients with bronchial asthma; 4. In the first 2 years of randomization, there was a history of drug abuse, drug addiction and alcohol abuse; 5. Artificial 2 receptor agonist or antagonist was used within 14 days before surgery; 6. Abnormal coagulation function; 7. Abnormal liver function; 8. Abnormal kidney function; 9. Allergic to dexmetomidine hydrochloride components or components; 10. Women during pregnancy or lactation; 11. The researchers determined that the patient was not suitable for other conditions of the clinical trial.

Design outcomes

Primary

MeasureTime frame
Patient satisfaction;Ramsay;Drowsiness;Respiratory depression;Bradycardia;Xerostomia;

Countries

China

Contacts

Public ContactZheng Jinwei

Ningbo 2nd Hospital

zjw_1007@163.com+86 13777112140

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026