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Effects of permissive hypercapnia on postoperative delirium in elderly patients with lacunar infarction under general anesthesia

Effects of permissive hypercapnia on postoperative delirium in elderly patients with lacunar infarction under general anesthesia

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017403
Enrollment
Unknown
Registered
2018-07-28
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lacunar cerebral infarction

Interventions

control group:Standard treatment
permissive hypercapnia group:permissive hypercapnia

Sponsors

the Third Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) Elderly patients with cerebral infarction receiving posterior lumbar decompression bone grafting and internal fixation under general anesthesia, American Society of Anesthesiologists physical status classes I or II.

Exclusion criteria

Exclusion criteria: (1) Operation time is longer than 3 hours; (2) The intraoperative blood loss is more than 800ml; (3) The operation is cancelled for various reasons. (4) with history of traumatic brain injury, neurological diseases and alcohol abuse; (5) with cognitive dysfunction, no severe vision or hearing impairment and obvious abormality od heart, lung, liver and kidney function.

Design outcomes

Primary

MeasureTime frame
s100ß;BDNF;—

Countries

China

Contacts

Public ContactQiujun Wang

the Third Hospital of Hebei Medicl University

13933178001@163.com+86 18533112929

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026