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Effect of zusanli injection of neostigmine on gastrointestinal function in severe patients

Effect of zusanli injection of neostigmine on gastrointestinal function in severe patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017379
Enrollment
Unknown
Registered
2018-07-27
Start date
2018-10-01
Completion date
Unknown
Last updated
2018-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Severe patients with gastrointestinal dysfunction

Interventions

B:neostigmine was injected into zusanli
C:neostigmine injection of simin

Sponsors

TaizhouTraditional Chinese Medicine Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. to be included in the severe disease area, which is in line with the diagnosis of acute gastric injury and the concept of "AGI" proposed by the European society of severe medicine (ESICM) in 2012; 2. acute physiology and chronic health evaluation II (APACHE II) score > 10 points; 3. aged 18-80 years old; 4. sequential organ failure estimation (SOFA) score > 8; 5. to accept the experimental study and complete the signature of family members.

Exclusion criteria

Exclusion criteria: 1. pregnant or lactating women; 2. No possibility of survival in 24-72 hours; 3. failure to accept or withdraw from the study; 4. patients with acute gastrointestinal dysfunction who improve by themselves; 5. patients with contraindications of neostigmine use; 6. patients with diarrhea; 7. with history of chronic gastropathy.

Design outcomes

Primary

MeasureTime frame
Gastric emptying;Gastric volume shrinkage;Intestinal flora;electrogastrogram;Before the albumin;

Secondary

MeasureTime frame
borborygmus;Electroencephalogram;Bedside tablet;

Countries

China

Contacts

Public ContactFangyu Yu

TaizhouTraditional Chinese Medicine Hospital

zqz1976@163.com+86 13867697189

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026