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The effect of stretch-Induced lncRNA on osteogenic differentiation in hPDLSCs

The effect of stretch-Induced lncRNA on osteogenic differentiation in hPDLSCs

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017350
Enrollment
Unknown
Registered
2018-07-25
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteogenic differentiation of human periodontal ligament stem cells

Interventions

Case series:mechanical stretching on hPDLSCs

Sponsors

Stomatological Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
12 Years to 24 Years

Inclusion criteria

Inclusion criteria: 1. Patients age range is 12-24 years old; 2. Due to orthodontic removal of permanent premolars; 3. No periodontal disease and dental pulp disease or dental caries.

Exclusion criteria

Exclusion criteria: 1. The patient's age is not in the group; 2. The extracted teeth have no roots or short roots; 3. Destroy the integrity of the tooth during tooth extraction; 4. The extracted tooth has periodontal or dental pulp disease or dental caries; 5. Exfoliate in the air for more than 3 minutes after removal.

Design outcomes

Primary

MeasureTime frame
Expression of osteogenic related factors in periodontal ligament stem cells;—

Countries

China

Contacts

Public ContactWei Fulan

Stomatological Hospital of Shandong University

fulanwei777@126.com+86 13969169965

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026