post-traumatic ARDS
Conditions
Interventions
HFNC group:High-flow nasal cannula oxygen
NIV group:non-invasive ventilation
Sponsors
Northern Jiangsu People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients group one: 1. Within 24h after trauma; 2. 200mmHg < PO2/FiO2 = 300mmHg. Patients group two: 1. Within 24h after trauma; 2. 100mmHg < PO2/FiO2 = 200mmHg. Patients group three: 1. The patients are diagnosed as trauma patients. 2. The patients with endotracheal intubation must pass spontaneous breathing test (SBT), can be successfully extubated.
Exclusion criteria
Exclusion criteria: Patients group one: 1. Less than 18 years old; 2. The informed consent can not be obtained; 3. Other organ failure except lung; 4. Tracheotomy. Patients group two: 1. Less than 18 years old; 2. The informed consent can not be obtained; 3. Severe ARDS requiring immediate endotracheal intubation: respiratory frequency >40 times/min, severe hypoxia, PO2/FiO2 < 200mmHg,severe respiratory acidosis, Arterial blood PH <7.25, GCS<8; 4. There are NIV taboos: oral and facial trauma, poor expectoration ability, active gastrointestinal bleeding. 5. Other organ failure except lung; 6. Tracheotomy. Patients group three: 1. Less than 18 years old; 2. The informed consent can not be obtained; 3. There are NIV taboos: oral and facial trauma, poor expectoration ability, active gastrointestinal bleeding. 4. Tracheotomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| arterial blood gas;respiratory rate;blood pressure;change and time of respiratory support;whether invasive ventilation (endotracheal intubation) and time; | — |
Secondary
| Measure | Time frame |
|---|---|
| dyspnea score;comfort score;facial skin breakage;respiratory and extrapulmonary complications;length of stay in ICU;length of stay in hospital;discharge (death, healed / improved); | — |
Countries
China
Contacts
Public ContactLi Yujie
Northern Jiangsu People's Hospital
Outcome results
None listed