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Effectof postoperative Bifidobacterium lactis M8 on intestinal flora andimmune function in patients with colorectal cancer

Effectof postoperative Bifidobacterium lactis M8 on intestinal flora andimmune function in patients with colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017264
Enrollment
Unknown
Registered
2018-07-20
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Probiotics Group:Bifidobacterium lactis M8
2:Intestinal antimicrobials

Sponsors

Weihai Municipal Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. can complete laparoscopic radical resection of colorectal cancer; 2. preoperative pathology confirmed as colorectal cancer; 3. patients generally in good condition, without serious heart, lung, kidney, liver dysfunction and metabolic diseases; 4. no serious intestinal obstruction, intestinal perforation and enteritis before surgery; 5. no distant metastatic lesions were found before surgery; 6. did not receive radiotherapy or chemotherapy. 7. Informed and voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. There were intestinal obstruction and intestinal perforation before operation; 2. abdominal and pelvic B-ultrasound or CT and chest X-ray examination suggest that there is distant metastasis (M1); 3. previous history of colorectal surgery or radiotherapy and chemotherapy; 4. pre-treatment colonoscopy showed multiple primary colorectal cancer; 5. can not tolerate surgery due to important organ function; 6. Allergic to the test sample or obvious gastrointestinal symptoms such as intolerance; 7. Accept other clinical trial patients at the same time; 8. The researcher determined that the researcher could not complete the research on time.

Design outcomes

Primary

MeasureTime frame
Intestinal flora;Intestinal barrier function;Humoral immune function;cellular immune function;

Countries

China

Contacts

Public ContactZhang Huanhu

Weihai Municipal Hospital

18660377179@163.com+86 18660377179

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026