Childhood asthma
Conditions
Interventions
Experience group :Bifidobacterium lactis M8
control group:No Bifidobacterium lactis M8
Sponsors
Weihai Municipal Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. age 3 to 5 years old boy and girl; 2. had a history of asthma, shortness of breath, shortness of breath, or more than 24 hours of coughing, and had previously used bronchodilators to treat respiratory problems or had been diagnosed with asthma; 3. in line with the guidelines for diagnosis and prevention of bronchial asthma in children (2016), diagnostic criteria for asthma in children aged 6 years or younger.
Exclusion criteria
Exclusion criteria: 1. congenital diseases such as congenital heart disease and congenital immunodeficiency; 2. glucocorticoids, antihistamines and immunomodulators were used within 2 weeks before treatment; 3. during the follow-up period, those who stopped or adjusted the subjects randomly; 4. during follow-up period, antibiotics are needed for acute respiratory diseases such as pneumonia; 5. patients received other clinical trials at the same time; 6. suffering from chronic digestive system diseases, such as peptic ulcer, inflammatory bowel disease and severe liver disease; 7. patients with malignant tumors, such as hematological diseases; 8. allergic reaction to the sample or obvious gastrointestinal symptoms such as intolerance; 9. patients who refused to sign the informed consent form; 10. patients who took antibiotics during the follow-up period; 11. during the follow-up period, patients with irregular eating habits and more variable patients 12. chest radiographs showed pneumonia, bronchitis and other diseases; 13. in the near February, those who had diarrhea or who took probiotics preparations; 14. the use of antibiotics within 5 D before admission; 15. researchers believe that it is not suitable for the participants.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Asthma symptom score; | — |
Secondary
| Measure | Time frame |
|---|---|
| TRACK;DNA of gut microbiome;Eosinophil; | — |
Countries
China
Contacts
Public ContactZhang Bing
Weihai Municipal Hospital
Outcome results
None listed