severe pneumonia
Conditions
Interventions
combined group:pathogenic gene chip detection and pathogenic detection
control group:pathogenic detection
Sponsors
Ningde municipal hospital Affiliated to Fujian Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Provide signed informed consent, aged 18 to max years, clinical symptoms suggestive of community-acquired pneumonia, acquired outside of the hospital or less than 48 hours after hospital admission, met SCAP criteria (defined by the American Thoracic Society) fulfilled three or more of the following criteria: PaO2/FiO2 ratio =250 mmHg, respiratory rate =30 breaths/min, blood urea nitrogen (BUN) >20 mg/dL, leukopenia (white blood cell count (WBC) <4000 cells/ mm3) not due to other causes, thrombocytopenia (platelet count<100,000 cells/mm3), hypothermia (core temperature <36 degree C), new onset mental confusion, receiving treatment with vasopressors at therapeutic doses after adequate fluid resuscitation, or radiographic findings on new pulmonary infiltrate(s) consistent with CAP diagnosis. Patients with pneumonia of sufficient severity requiring ICU management and patients meeting at least one of the severity criteria, such as receiving mechanical ventilatory support or septic shock with the need for vasopressors, were also included in the study).
Exclusion criteria
Exclusion criteria: Life expectancy was 48 hours or less, pregnant or lactating, diagnosed with lung tumors,acute myocardial infarction and stock could not complete the study judged by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| mortality;Index related with inflammation;Hospitalization time; | — |
Countries
China
Contacts
Public ContactCanhui Zhang
Ningde municipal hospital Affiliated to Fujian Medical University
Outcome results
None listed