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Exploring the diagnostic threshold of stroke volume variation in elderly patients undergoing laparoscopic radical gastrectomy and its guiding goal-directed fluid therapy feasibility: a prospective, randomized clinical trial

Exploring the diagnostic threshold of stroke volume variation in elderly patients undergoing laparoscopic radical gastrectomy and its guiding goal-directed fluid therapy feasibility: a prospective, randomized clinical trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017233
Enrollment
Unknown
Registered
2018-07-19
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic radical gastrectomy

Interventions

test group:6% hydroxyethyl starch(HES 130/0.4) 7ml/kg was infused range 15 to 20 minute
test group:SVV-directed goal-directed fluid therapy
Control group:conventional intraoperative fluid management

Sponsors

The Affiliated Hospital Of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age: 65 to 80 years old; 2. ASA grade II to III; 3. Body mass index 18-28kg/m2; 4. Hb>110 g/L; 5. No abnormalities in vital organs such as heart, lung, liver and kidney.

Exclusion criteria

Exclusion criteria: 1. Disagree to sign informed consent; 2. Coronary heart disease, arrhythmia, heart failure; 3. Peripheral vascular disease and arterial puncture contraindications; 4. Other systemic history of hypertension, diabetes, and mental illness.

Design outcomes

Primary

MeasureTime frame
Rate of change of stroke volume index;Arterial blood lactate value;Oxygen supply index;

Secondary

MeasureTime frame
central venous blood oxygen saturation;Central venous arterial blood pressure difference of carbon dioxide;stroke volume index;stroke volume variation;stroke volume;cardiac index;cardiac output;

Countries

China

Contacts

Public ContactCHEN Xiuxia

The Affiliated Hospital Of Xuzhou Medical University

cxxlxy@sina.com+86 15205200798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026