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Identification and popularization of specific mutation sites in Izumo1 and Juno protein coding regions in patients with sperm-egg binding disorders

Identification and popularization of specific mutation sites in Izumo1 and Juno protein coding regions in patients with sperm-egg binding disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017230
Enrollment
Unknown
Registered
2018-07-19
Start date
2018-09-18
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

Case-Control group:no

Sponsors

The Third Affiliated Hospital of Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
22 Years to 38 Years

Inclusion criteria

Inclusion criteria: Case group: Couples are primary infertility,eliminate common infertility factors. Eg: semen abnormalOvulation disorder; Fallopian tube obstruction Uterine factor,Immune fact. Fertilized egg failure or fertilization rate <30% in conventional IVF; Control group: Naturally conceived, normally born couple.

Exclusion criteria

Exclusion criteria: There are clear reasons for infertility. Eg: Male semen abnormal femaleOvulation disorder, Fallopian tube obstruction, Uterine factor, Immune factorand so on.

Design outcomes

Primary

MeasureTime frame
Izumo1 and Juno protein DNA level sequencing in peripheral blood of infertility patients;—

Countries

China

Contacts

Public ContactQinghua Zhang

The Third Affiliated Hospital of Army Medical University

zhangqh1123@163.com+86 13594013576

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026