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A study for the effect of intestinal microecological intervention on the risk of different hepatitis B progression

A study for the effect of intestinal microecological intervention on the risk of different hepatitis B progression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017212
Enrollment
Unknown
Registered
2018-07-17
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hepatitis B

Interventions

a: black control:NONE
b:Probiotics 2g/ day for 6 months (Probiotics Weileshu 1 package qd x 6 months)
c:Probiotics 4g/ day + Inulin for 3 months (Probiotics Weileshu 1 package bid+ Inulin 1 package bid x 3 months)
d:Probiotics 4g/ day + Inulin for 6 months (Probiotics Weileshu 1 package bid+ Inulin 1 package bid x 6 months)
hepatitis B virus carriers:Probiotics 2g/ day for 3 months (Probiotics Weileshu 1 package qd x 3 months)
hepatitis B virus carriers:none
HBV-related liver cancer:NONE
HBV-related liver cirrhosis:NONE

Sponsors

Shulan (Hangzhou) Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 17 to 80 years old patients, who were diagnosed with hepatitis B virus carriers chronic hepatitis B HBV-related liver cirrhosis and liver cancer patients, eat regularly and no use of antibiotics nearly 2 weeks.

Exclusion criteria

Exclusion criteria: 1) alcoholic hepatitis, drug hepatitis, autoimmune hepatitis and other viral hepatitis; 2) diabetes, hypertension, various nephritis, hyperlipidemia and various mental diseases; 3) colitis, inflammatory bowel disease, gastrointestinal bleeding and other diseases that seriously affect intestinal flora.

Design outcomes

Primary

MeasureTime frame
intestinal microecology;

Secondary

MeasureTime frame
HBsAg, HBeAg, HBeAb;

Countries

China

Contacts

Public ContactXu Wei

Shulan (Hangzhou) Hospital

zjuxuw@163.com+86 13805758825

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026