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Association between intensive blood pressure reduction and cerebral perfusion and outcome in patients with intracerebral hemorrhage

An investigator initiated and conducted, international, multicentre, randomised study of the association between intensive blood pressure reduction and cerebral perfusion and outcome in patients with intracerebral hemorrhage

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017201
Enrollment
Unknown
Registered
2018-07-17
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intracerebral hemorrhage

Interventions

intensive blood pressure reduction group:intensive blood pressure reduction
routin blood pressure management group:routin blood pressure management

Sponsors

Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. aged =18 years; 2. Acute stroke syndrome that is due to presumed spontaneous ICH, confirmed by clinical history and a CT scan without/without contrast, and if an CT angiogram is also undertaken as part of routine care; 3. Presentation to hospital within 6 hours of stroke onset.

Exclusion criteria

Exclusion criteria: 1. Definite evidence that the ICH is secondary to a structural abnormality in the brain or previous thrombolysis; 2. Baseline CTP>6 hours; 3. A high likelihood that the patient will not adhere to the study treatment and follow-up regimen.

Design outcomes

Primary

MeasureTime frame
a shift analysis of mRS scores;—

Secondary

MeasureTime frame
cerebral blood flow;cerebral blood volume;time to peak;a shift analysis of NIHSS scores;Death and disability (mRS 3-6);EQ-5D;—

Countries

China

Contacts

Public ContactYuping Tang

Huashan Hospital, Fudan University

tangyuping39@hotmail.com+86 13764480396

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026