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Multiple Boluses of Oral and Topical Tranexamic Acid to Reduce Hidden Blood Loss After primary knee arthroplasty: A Randomized Clinical Trial

Multiple Boluses of Oral and Topical Tranexamic Acid to Reduce Hidden Blood Loss After primary knee arthroplasty: A Randomized Clinical Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017185
Enrollment
Unknown
Registered
2018-07-17
Start date
2018-07-16
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total knee replacement

Interventions

A: 2 hours before skin incision and 1 g at 3 hours after operation
B: Intraoperative use of local TXA 3G

Sponsors

West China Hospital, Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Osteoarthritis requires TKA surgery

Exclusion criteria

Exclusion criteria: Infection, hypertension, anemia, revision surgery

Design outcomes

Primary

MeasureTime frame
blood loss;range of motion;inflammatory;cost;—

Countries

China

Contacts

Public ContactYuangang Wu

West China Hospital, Sichuan University

wuyuangang23@163.com+86 18328318171

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026