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The effect of botulinum toxin injection in different target muscles in the treatment of spastic foot drop and talipes varus after stroke

The effect of botulinum toxin injection in different target muscles in the treatment of spastic foot drop and talipes varus after stroke

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR1800017177
Enrollment
Unknown
Registered
2018-07-16
Start date
2018-08-01
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

1:tibialis anterior muscle combined with injection BTX-A 30U
2:No

Sponsors

the Affiliated Hospital of Qiingdao University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for stroke developed by the 4th National Conference on Cerebrovascular Diseases in 1995. It is confirmed by CT or MRI as cerebral infarction or cerebral hemorrhage, and both are supratentorial lesions 2. Between 18 and 80 years of age; 3. First onset, unilateral hemiplegia; 4. With spastic foot drop and talipes varus in hemiplegic lower extremity; 5. post stroke duration of = 6 months ,and the Modified Ashworth scale of hemiplegic lower extremity =?+; 6. Participants or their parents agrees to receive the treatment and provide written informed consent

Exclusion criteria

Exclusion criteria: 1. Severe allergies, history of allergies to alcohol or botulinum toxin; 2. Severe cardiovascular disease or liver and kidney dysfunction; 3. High blood pressure instability; 4. Local infection at the injection site; 5. Serious cognitive dysfunction or mental disorder can not complete or cooperate with the study; 6. Taking antispasmodic drugs recently.

Design outcomes

Primary

MeasureTime frame
MAS;FMA;the time of 10m;

Countries

China

Contacts

Public ContactZhang Yongxiang

the Affiliated Hospital of Qiingdao University

zhang.yxl@163.com+86 18661806351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026