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A prospective, multicenter study of the effects of hyperglycemia on prostate cancer progression, urination, and sexual function in Chinese population

A prospective, multicenter study of the effects of hyperglycemia on prostate cancer progression, urination, and sexual function in Chinese population

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR1800017170
Enrollment
Unknown
Registered
2018-07-16
Start date
2016-09-01
Completion date
Unknown
Last updated
2018-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

prostate cancer

Interventions

High blood glouce group:Nil
Normal blood glucose group:Nil

Sponsors

Shenzhen Hospital of Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients who have undergone prostate biopsy or have been treated with TURP for diagnosis of prostate cancer Prostate biopsy indications: (A) Prostate nodules found on rectal examination, any PSA value; (1) PSA> 10 ng/ml, any f/t PSA or PSAD value; (2) PSA 4-10ng/ml, abnormal f/tPSA or PSAD values; (3) PSA 4-10 ng/ml, normal f/t PSA or PSAD, abnormal findings on ultrasound or MRI (where f/tPSA =0.25-0.27 or PSAD>0.15 is abnormal); 2. Voluntary participants and signing informed consent patients; 3. Patients who can communicate well with the investigator and follow the entire follow-up requirement 4. Blood glucose standard: After excluding stress, strenuous exercise, infection and other predisposing factors, two fasting blood glucose levels were greater than 6.1 mmol/L for the hyperglycemia group, and fasting blood glucose levels below 5.6 mmol/L for the normoglycemic group. (Normal adult fasting blood glucose is 3.9-6.1mmol/L, less than 11.1 mmol/L at 2 hours after meal).

Exclusion criteria

Exclusion criteria: 1. prostate biopsy but no prostate cancer tissue; 2. Poor compliance, patients who refused follow-up or lost to follow-up; 3. Exclude hyperglycemia caused by predisposing factors such as stress, strenuous exercise, and infection.

Design outcomes

Primary

MeasureTime frame
blood glucose;Gleason score;Prostate volume;Prostate specific antigen density;

Secondary

MeasureTime frame
age;Height and body mass index;Clinical stage;

Countries

China

Contacts

Public ContactWen Xingqiao

Department of Urology, Shenzhen Hospital of Southern Medical University

18922102731@qq.com+86 13825159838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026