Acute Ischemic Stroke
Conditions
Interventions
Sponsors
The Second Institute of Clinical Medicine,Guangzhou University of Chinese Medicine(Guangdong Provincial Hospital of Chinese Medicine)
Eligibility
Sex/Gender
Male
Age
18 Years to 96 Years
Inclusion criteria
Inclusion criteria: 1. According to the American Stroke Management Guide in 2018, patients diagnosed with acute ischemic stroke. 2. The patient's had received MRI(T1, T2, DWI, ADC) examination within 5 hours before treatment and determined the presence of "ischemic penumbra" with DWI and T2Flair mismatch. 3. The patient's had received CT scan of the head before treatment to exclude patients with cerebral hemorrhage 4. From symptom onset to treatment no more than 24 hours. 5. CT examination was performed within 12 hours after surgery,NIHSS scores were checked 5 days after treatment and one month after discharge.
Exclusion criteria
Exclusion criteria: (1) A history of intracranial hemorrhage in the last 3 weeks, cerebral arteriovenous stenosis or aneurysm was found previously and without intervention or surgery; (2) Uncontrollable refractory hypertension (systolic blood pressure=185mmHg, or diastolic blood pressure=110mmHg); (3) known to be allergic to contrast agents; (4) blood glucose 22.0mmmol / L; (5) Acute hemorrhagic constitution, including clotting factor deficiency, international normalized ratio (INR) > 1.7 or platelet count < 100 x 10^9/L; (6) Had history of arterial puncture in incompressible areas within the last 7 days; Major surgery or severe trauma history in the last 14 days; Gastrointestinal or urethral bleeding in the last 21 days. (7) Had diseases that increase the risk of bleeding in the last 3 months, such as severe craniocerebral trauma, severe liver disease, ulcerative gastrointestinal disease, etc.Had surgery, substantial organ biopsy, active bleeding within 1 month; (8) Suspected septic embolism or bacterial endocarditis; (9) Life expectancy <90 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy;Sensitivity; | — |
Countries
China
Contacts
Public ContactGuo-qing Liu, Bo Liu
The Second Institute of Clinical Medicine, Guangzhou University of Chinese Medicine(Guangdong Provincial Hospital of Chinese Medicine)
Outcome results
None listed